2016 Publications

Trott DW, Henson GD, Ho MH, Allison SA, Lesniewski LA, Donato AJ. Age-related  arterial immune cell infiltration in mice is attenuated by caloric restriction or voluntary exercise. Exp Gerontol. 2016 Dec 22. pii: S0531-5565(16)30348-5. doi: 10.1016/j.exger.2016.12.016. [Epub ahead of print] PubMed PMID: 28012941; PubMed Central PMCID: PMC5481497.

Machin DR, Leary ME, He Y, Shiu YT, Tanaka H, Donato AJ. Ultrasound Assessment of Flow-Mediated Dilation of the Brachial and Superficial Femoral Arteries in Rats. J Vis Exp. 2016 Nov 3;(117). doi: 10.3791/54762. PubMed PMID: 27842366; PubMed Central PMCID: PMC5226081.

Machin DR, Clifton HL, Garten RS, Gifford JR, Richardson RS, Wray DW, Frech TM, Donato AJ. Exercise-induced brachial artery blood flow and vascular function is impaired in systemic sclerosis. Am J Physiol Heart Circ Physiol. 2016 Dec 1;311(6):H1375-H1381. doi: 10.1152/ajpheart.00547.2016. Epub 2016 Sep 30. PubMed  PMID: 27694218; PubMed Central PMCID: PMC5206341.

Lesniewski LA, Seals DR, Walker AE, Henson GD, Blimline MW, Trott DW, Bosshardt GC, LaRocca TJ, Lawson BR, Zigler MC, Donato AJ. Dietary rapamycin supplementation reverses age-related vascular dysfunction and oxidative stress, while modulating nutrient-sensing, cell cycle, and senescence pathways. Aging Cell. 2017 Feb;16(1):17-26. doi: 10.1111/acel.12524. Epub 2016 Sep 22. PubMed PMID: 27660040; PubMed Central PMCID: PMC5242306.

Hazra S, Henson GD, Morgan RG, Breevoort SR, Ives SJ, Richardson RS, Donato AJ, Lesniewski LA. Experimental reduction of miR-92a mimics arterial aging. Exp Gerontol. 2016 Oct;83:165-70. doi: 10.1016/j.exger.2016.08.007. Epub 2016 Aug 11. PubMed PMID: 27523918; PubMed Central PMCID: PMC5013538.

Beyer AM, Freed JK, Durand MJ, Riedel M, Ait-Aissa K, Green P, Hockenberry JC, Morgan RG, Donato AJ, Peleg R, Gasparri M, Rokkas CK, Santos JH, Priel E, Gutterman DD. Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation. Circ Res. 2016 Mar 4;118(5):856-66. doi:  10.1161/CIRCRESAHA.115.307918. Epub 2015 Dec 23. PubMed PMID: 26699654; PubMed Central PMCID: PMC4772813.

Walker AE, Morgan RG, Ives SJ, Cawthon RM, Andtbacka RH, Noyes D, Lesniewski LA, Richardson RS, Donato AJ. Age-related arterial telomere uncapping and senescence is greater in women compared with men. Exp Gerontol. 2016 Jan;73:65-71. doi: 10.1016/j.exger.2015.11.009. Epub 2015 Nov 19. PubMed PMID: 26602606; PubMed Central PMCID: PMC4792184.

Trinity JD, Barrett-O’Keefe Z, Ives SJ, Morgan G, Rossman MJ, Donato AJ, Runnels S, Morgan DE, Gmelch BS, Bledsoe AD, Richardson RS, Wray DW. Endogenous endothelin-1 and femoral artery shear rate: impact of age and implications for atherosclerosis. J Hypertens. 2016 Feb;34(2):266-73. doi: 10.1097/HJH.0000000000000777. PubMed PMID: 26599223; PubMed Central PMCID: PMC5380231.